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In this study, we firstly confirmed that compared with RBITC-GLP-1RAs@NPs, RBITC-GLP-1RAs@NPs-WYRGRL could effectively target tissues with abundant cartilage, such as joints, and could be retained in cartilage tissues more effectively, and thus be excreted by the kidneys less

Severe or persistent symptoms may indicate complications such as pancreatitis or gallbladder disease, which require prompt medical evaluation

Then induction of p38 activation was observed 36 h after PH and remained stable until 168 h (Figure 6b)

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It does this without raising IGF-1 levels, without affecting insulin sensitivity, and without promoting tissue growth beyond fat metabolism