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Poornima I, Brown SB, Bhashyam S, Parikh P, Bolukoglu H, Shannon RP: Chronic glucagon-like peptide-1 infusion sustains left ventricular systolic function and prolongs survival in the spontaneously hypertensive, heart failure-prone rat

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Phase 2: weeks 5 through 12 (building momentum) By week five, most people have adapted to the initial dose and gastrointestinal side effects have diminished significantly

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The STEP clinical trial program enrolled a majority-female population (approximately 75% in STEP-1), making it one of the more sex-representative obesity pharmacotherapy datasets available

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