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0.5 mL of medium was removed from each well, and replaced with medium containing (i) FITC-insulin alone (concentration 100 L/mL), (ii) FITC-insulin with sodium chenodeoxycholate (1 mg/mL) or (iii) FITC-insulin with sodium chenodeoxycholate (2 mg/mL)

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Five mechanistic axes are documented: 1