1 Introduction Sepsis-associated encephalopathy (SAE) represents a severe complication of sepsis, defined by diffuse brain dysfunction without direct central nervous system (CNS) infection (Young et al., 1990) and the overall mortality rate remains high at 25%50%, despite advances in critical care
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For peptide manufacturers and GLP-1 CMOs and CDMOs, this creates a new challenge: scaling complex peptide synthesis while maintaining the purity, consistency, and cost efficiency expected for commercial APIs
Zhang, D., Huang, W., Dai, B., Zhao, T., Ashraf, A., Millard, R