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Abstract Background: The term post-cycle therapy (PCT) often appears in bodybuilding forums in the context of anabolic-androgenic steroids (AAS) cessation

It was first described and also named in 1921 (Hopkins) and in 1935 it could be synthesized and its structure was definitively established

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Lastly, it is worth highlighting the development of trials based on innovative therapies developed within the region, which are on par with those conducted in high-income countries, such as dendritic cell-based vaccines used as neoadjuvant treatment, demonstrating the regions potential to develop therapies tailored to its population (190, 191)

One hundred and forty companies passed the initial screening