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For example, tirzepatide may reduce the effectiveness of oral contraceptives, and patients taking warfarin with any GLP-1 receptor agonist should consider more frequent INR monitoring when starting or stopping therapy

Monitor your urine colour pale straw indicates adequate hydration, whilst dark yellow suggests insufficient fluid intake

Black or tarry stool, visible blood in the stool, vomiting blood, severe abdominal pain, unexplained weight loss, persistent fever, anemia, or progressive swallowing difficulty should be evaluated appropriately

Search authorised UK medicines Human Medicines Regulations 2012, Regulation 279

One promising avenue of treatment is the use of GLP-1 medications after VSG to help control and maintain weight loss over the long term