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( 10.2337/db08-1193) [DOI] [PMC free article] [PubMed] [Google Scholar] Noyan-Ashraf MH, Shikatani EA, Schuiki I, Mukovozov I, Wu J, Li RK, Volchuk A, Robinson LA, Billia F, Drucker DJ, et al

This antioxidant could reduce NF-B and iNOS expression levels in the rats' livers (Fouad and Jresat, 2012)

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Figure 1 The immunomodulatory functions of melatonin can have proinflammatory and anti-inflammatory effects under different inflammatory conditions and can improve the bodys resistance and resilience to exogenous or endogenous antigens (52)

Additional risks include gallbladder disease and acute kidney injury in the setting of severe gastrointestinal adverse events