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Reflecting the fact that GLP-1 receptors have been found to be substantially more abundant in the human lung than other organs, GLP-1 drugs are now also being explored for the treatment of acute and chronic pulmonary disease

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35 This method used leftover blood spots previously extracted with methanol for acylcarnitine and amino acid analysis

Building on this evidence base, future work should remain deliberately focused on standardizing stereochemically controlled measurement pipelines, establishing causal writer/eraser/readersubstrate relationships and their effector consequences with orthogonal perturbations, and mapping heterogeneity through cross-cohort Klasubtype atlases that connect MCT1/MCT4 balance, LDH isoforms, and lactylation fingerprints to clinically actionable subgroups and companion diagnostics [78, 88, 393, 394]

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