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Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities

The items use a 5-point Likert scale ranging from 0 (Not at all) to 4 (Extremely)

The physical examination included: (i) ankle reflexes, which were scored as normal (0 point), present only with reinforcement (1 point), or totally absent (2 points)

Additional studies will be needed to delineate the role of oxidative stress in determining the magnitude and duration of NLRP3 activation following vaccination with and without adjuvanted vaccines and the types of adjuvants

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