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In heart failure patients with preserved ejection fraction, semaglutide improves exercise capacity and NT-proBNP levels

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2024 May 27;14(8):3339-3357

Based on the agonist-AR LBD complex structure, it is believed that favorable H bonding between the ligand and AR T877, N705, Q711, and R752 and a hydrophobicity within a proper range are critical for ligands to bind to the AR with high affinity

the slices were deparaffinized and stained with hematoxylin a After deparaffinization, the slices were stained with hematoxylin and eosin (H.E.), and the slices were sealed and observed and photographed with an orthogonal fluorescence microscope (Leica DM5500B)