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Silent information regulator 1 (Sirt1), an anti-inflammatory and anti-oxidative protein (316), increases the production of NO by activating endothelial NOS (eNOS) in endothelial cells in response to shear stress (317)

The Lancet HIV, online ahead of print, 2019.

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The secreted IL-10 cytokine values measured in the supernatant collected from cells stimulated with LPS and treated with the test products are reported in Table 3, which are expressed in terms of percentage (%) with respect to the cytokine level measured in the supernatant collected from control cells, stimulated with LPS, and incubated with the medium alone