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Lidocaine stabilizes excitable membranes by reversible blockade of voltage-gated fast sodium channels in their open and inactivated states, thereby reducing the rate of phase 0 depolarization and suppressing spontaneous impulse generation in ectopic foci

Unlike gastroparesis caused by irreversible nerve damage (such as that seen in long-standing diabetes or post-surgical complications), the delayed gastric emptying induced by Ozempic results from ongoing receptor activation

In those patients, the goal is not to accelerate healing past the point of safety, but to support the quality of repair during the remodeling phase, particularly for soft tissue that was disrupted during the procedure

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Oral-contraceptive interaction and immunogenicity backup or non-oral contraception for 4 weeks after initiation and each escalation