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Neither peptide is approved for human use, no dosing has been validated in controlled human trials, and the information here is not a recommendation

Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)

Shaking can be catastrophic for the peptide

Why People Choose B12 Injections at Home Vitamin B12 is essential for energy, nerve function, and red blood cell production

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