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Researchers included observational studies from four major databases, including case-control, cross-sectional and cohort studies, with data on the risk estimates for cataract, uveitis, dry eye disease, glaucoma, retinal vein occlusion (RVO), conjunctivitis, meibomian gland dysfunction and blepharitis

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Also, additional research on the isolated effect of 1,25-Dihydroxyvitamin D3 on autoantibodies production such as IgA, IgE, IgG and the synergistic effect of probiotics, vitamin D, and ginger bioactive on SLE disease development must be carried out