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the 2.88 mg/kg amount produced the larger effect on neuroinflammatory cytokine markers and PI3K/AKT pathway activation [5]

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Oxaliplatin binds to both erythrocytes and serum albumin: platinum complexes formed via erythrocyte binding have a half-life of up to 1250 days, while agents bound to serum albumin can form a long-term reservoir in the body, continuously releasing free platinum to target tissues such as peripheral nerves, and ultimately mediating chronic cumulative neurotoxicity

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This preparation contains 10 mg of high purity lyophilized compound supplied in a sealed research vial