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It is understood, that in such polyhydroxyl, polyamino, carboxylic acid, sulfuric acid, and like linkers that include free hydrogens bound to heteroatoms, one or more of those free hydrogen atoms may be protected with the appropriate hydroxyl, amino, or acid protecting group, respectively, or alternatively may be blocked as the corresponding pro-drugs, the latter of which are selected for the particular use, such as pro-drugs that release the parent drug under general or specific physiological conditions

Geleta BE, Seyoum G

Nine out of ten times, people will do the first two things, but you can use the topical product too so levels can be enhanced faster

A vitamin B12 injection skips the middle step

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