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i , Representative fluorescent micrographs of intestinal nuclear permeability in wild-type, cco-1 RNAi, or fer-2 (5 mM) supplementation animals injected with 70 kD dextran in the cytosol and corresponding fluorescence intensity distribution curve

Proc Natl Acad Sci USA 95 , 1321713220 (1998)

Jerne had in fact spent his final months in Pasadena trying to answer this question after Jean Weigle, a Swiss molecular biologist at Caltech, pressed him on the issue in the winter of 1954-1955

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