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Common side effects of the drug include: Tingling in the hands and feet (paresthesia) Drowsiness or fatigue Dizziness or lightheadedness Memory problems Loss of appetite Nausea Diarrhea Altered sense of taste Nervousness Upper respiratory infection Speech problems Slowed reactions Abdominal pain Abnormal vision Fever Decreased feeling/sensitivity of the skin In many cases, topiramate side effects are most noticeable when starting the medication or increasing the dose

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These were described in conference abstracts and later reviews, but not published as full papers

Current research focuses on enhancing transdermal absorption through various technologies including microneedle patches, chemical penetration enhancers, and modified drug formulations