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demonstrated that the reduction in oxidative stress induced by metformin (dose: 1 mM) is associated with the downregulation of NADPH Oxidase 4 (NOX4) expression

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Moreover, the (KLAKLAK)2 peptide guided by CD44v6-binding (CNLNTIDTC and CNEWQLKSC), Her-2-binding (YCDGFYACYMDV), prostate tumor-targeting (SMSIARL), and bladder tumor-targeting (CSNRDARRC) peptides efficiently inhibited tumor growth with minimal effects on normal tissues 55,56,57,58,59

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Donate References Benatta M, Kettache R, Buchholz N, Trinchieri A