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The negative reaction is associated with a perceived failure to achieve an average of 25%, considered a benchmark target.[2] The panel remarked that, while efficacy is clearly important, any impetus to increase potency must be considered considering the potential for enhanced cost and worsening side effects

If you have a known copper allergy (sometimes identified through reactions to copper jewelry), patch test any GHK-Cu product on your inner forearm for 48 hours before applying it to your face