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2) Administration of a combination of cagrilintide and semaglutide resulted in significant weight loss, as well as reductions in HbA1c levels in type 2 diabetic participants

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Cagrilintide, on the other hand, was more balanced in how it activated both sensors

Although protein levels were not reported, in this study, mRNA levels for 5alpha-reductase and 3alpha-HSD were noted to be reduced in the hippocampus of these rats, which also had impaired performance on a hippocampal-dependent memory test and increased sensitivity to the anxiolytic effects of alphaxalone (303)