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274 Treatment of monocyte-derived DCs with the methyltransferase inhibitor 5-azacytidine increases the levels of the costimulatory molecules CD40 and CD86, which, in turn, induce activated T cells to express the cytokines IFN- and IL-17A

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Beginners are usually advised to start with a daily dose of 0.25mg-0.5mg, slowly raising the dosage to the desired pigmentation over time