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doi: 10.1038/nri3843

While our gastrointestinal tract produces several digestive enzymes, the most common ones are amylase, lipase, protease, and lactase

these molecules activate host receptors (AhR, TLR2) to promote IL-10 production and anti-inflammatory phenotypes in the mucosa, thereby reinforcing barrier function and limiting translocation of pro-inflammatory molecules such as LPS (98)

We basically looked at the traditional (pharmacy benefit) model and we said we are not getting the cost efficiency [and] the affordability that we need to make sure that our members are getting access to medications the way they need to get access to medications

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