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GLP-1 receptor agonists such as semaglutide and liraglutide work by enhancing satiety, reducing appetite, and improving metabolic parametersmechanisms that complement the physiological effects of surgery

No approval for either

The risk is not toxicity

United States Legal Status and Compounded Peptide Considerations FDAs May 2026 bulk-substance document lists GHK-Cu except for injectable routes of administration as a 503A category 1 substance under evaluation and says FDA intends to consult the Pharmacy Compounding Advisory Committee before the end of February 2027 about potential inclusion on the 503A bulks list [19]

Tirzepatide may be appropriate if: You have tried semaglutide with good tolerance but want to see if tirzepatide would enhance your weight loss results, you have type 2 diabetes but have not had adequate glucose control on other GLP-1 medications, or have sleep apnea