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Long-term treatment with pegvisomant as monotherapy in patients with acromegaly: experience from acrostudy

This process of protein deposition is somewhat comparable, but occurs slower in Alzheimers disease, leading to dementia much later in life

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Despite promising Phase 2 results and an excellent safety profile, the compound could not demonstrate sufficient efficacy in the larger confirmatory trial to justify the investment required for continued pharmaceutical development toward regulatory approval

Replenza reviews are genuinely mixed, and understanding why requires looking at the positive and negative feedback separately