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Inflammatory bowel disease, which is a condition that causes long-term inflammation in the digestive tract, can also make you bleed rectally

Because of that, once you stop the medication, your body returns to its natural signals

If semaglutide changes how frequently or easily a person passes stools, it could have long-term effects on anorectal health

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branded medication costs vary by insurance (per Mochi's published rates as of July 2026)