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doi:10.1016/j.rmed.2017.03.011 10BerkowitzAL, SamuelsMA

Obesity is associated with several health complications, including an increased risk of co-morbidities, including type 2 diabetes, cardiovascular disease, chronic kidney disease (CKD) and metabolic dysfunction-associated steatohepatitis (MASH)

Semaglutide (Wegovy) and liraglutide (Saxenda) are the primary weight loss injections licensed in the UK for weight management, and both list headaches as a recognised adverse effect in their Summary of Product Characteristics (SmPC)

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UK pharmacy and clinical practice, guided by the Specialist Pharmacy Service (SPS), generally discourages the routine use of multi-dose vials and requires that any in-use shelf life and storage conditions follow validated, product-specific data