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Additionally, by redirecting metabolism of fatty acids to a carnitine-independent one in the peroxisomes, it reduces the formation of acyl/acetyl-carnitines implicated in cardiac pathology potentially protecting against vascular trauma in ultra-athletes

They are better viewed as potential complements to conventional treatment, not substitutes

10.1038/518466a Nature 116 ShettyA

Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors

Therapy duration varies from acute correction in metabolic crises to lifelong supplementation in primary systemic deficiency