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GPX7 can transmit oxidative stress signals by forming disulfide bonds between its catalytic sites Cys57 and Cys86 residues, and this oxidized form of GPX7 can bind to each other with GRP78 and form covalent bond intermediates between Cys86 of GPX7 and Cys41/Cys420 of GRP78 (Wei et al., 2012) (Figure 5)

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In normal redox balance and low B 6 status, Se-GSH-Px was lower with organic selenium than with inorganic selenium, but both sources of selenium gave equivalent Se-GSH-Px responses when the diet was supplemented with vitamin B 6 (Figure 6)

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Carbonylation of adipose proteins in obesity and insulin resistance