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[Abstract] Pharmaceuticals (Basel)

In the pathological state of ischemic stroke, inflammatory signals released by dead neurons or cytokines and chemical inducers secreted by microglia under stress could drive circulating lymphocytes to recruit to the damaged brain (61, 62)

Safety considerations include pregnancy and breastfeeding status, existing medical conditions, and concurrent medicines

Int J Mol Sci 23(19):11177 Berry CE, Hare JM (2004) Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications

In addition, studies with other diet-induced MASLD animal models showed downregulation of GPx mRNA expression (Li et al