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Resists oxidative stress

One important feature of mitochondrial permeabilization is the loss of function resulting in the inability of mitochondria to synthesize ATP through the OXPHOS

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Glutathione is composed of three amino acids: cysteine, glutamine, and glycine

This multifactorial etiology supports the view of ALS as a point of no return disease, where the failure of therapies to halt disease progression reflects the deep complexity of its biology [59, 60]