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Upon reanalysis, we found that, in the sensitivity analysis, all PTsexcept for vitreous floaters (ROR = 0.78)still exhibited ROR values greater than 1, indicating that SLE did not confound the associations observed for the remaining seven PTs

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Some studies have reported that depression caused by chronic stress disrupts the BDNFtropomyosin related kinase B (TrkB) receptor signaling pathway in the PFC and hippocampus, and ultimately contributes to impaired synaptic maturation, synaptic protein synthesis, and glutamate receptor cycling (Collingridge et al., 2010

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Strength training, in particular, helps build muscle, which increases metabolic rate and supports fat loss