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Emerging strategies focus on mitochondrial-specific antioxidants (e.g., MitoQ, SS-31), which have shown promise in preclinical and early-phase clinical trials by reducing mtROS and improving endothelial function in diabetic patients (Mason et al., 2022)

CPAP treatment can decrease the frequency of nocturia and therefore improve the quality of life (107)

Vitamin B12 injections can be accessed via the NHS

These findings highlight the interplay between hormonal and genetic factors in shaping sex-specific trajectories of AD onset and progression