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Besides GCG gene and GCK we identified AKT1 as the top interactor in the GLP1RA network

To further validate our transcriptomic findings at the protein level, we assessed expression of key enzymes involved in glutathione biosynthesis, including GCLC, GCLM, and GLRX ( Figures 6E - G )

Additionally, individual patient-level meta-analyses could enhance our understanding of demographic and clinical factors influencing treatment efficacy

Aortic aneurysms, chronic kidney disease and metalloproteinases