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Nevertheless, the consistency of the signal across multiple analyses strengthens the case for prospective investigation

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Other participants in the TCA cycle are also more active in KRAS-mutant tumors, particularly in pancreatic ductal adenocarcinoma (PDAC), where the increased expression of GOT1/2 supports glutamine metabolism while producing NADPH to maintain REDOX balance [50]

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Transl Psychiatry 7:e1003

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