Ive sprinkled in HMG over that same time frame, so the current protocol has been steady for a month
performed a cross-trial analysis using data from clinical trials of GLP-1RAs (ELIXA, LEADER, SUSTAIN-6, EXSCEL, HARMONY, REWIND, PIONEER-6 [59], and AMPLITUDE-O), SGLT2is (CANVAS and CREDENCE), and finerenone (FIDELIO-DKD and FIGARO-DKD) to estimate the effects of the triple combination therapy of GLP-1RA, SGLT2i, and finerenone using the actuarial method [60]
References Goodman & Gilmans Pharmacological Basis of Therapeutics Katzung BG
Pre-mixed blends are best reserved for the maintenance phase once both compounds are at stable target doses
The mitochondrial membranes are impermeable to coenzyme A(CoA) esters and long-chain fatty acids, binding of L-carnitine to acetyl groups via carnitine acyltransferase is essential for the shuttle of the acetylated fatty acids into the mitochondria and their subsequent oxidation