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Obes Res 2005

The hormone is involved in the release of feel-good hormones like serotonin, so as estrogen fluctuates and drops through perimenopause, your brain has a harder time keeping your emotions regulated

This characteristic may improve renal function by increasing renal blood flow, urine flow rate, preventing elevated plasma creatinine, reducing tubular necrosis, increasing renal interstitial fluid and glomerular filtration rate, and cytoprotective and anti-inflammatory effects [12,13], and may improve glomerular hyperosmosis in patients with T2DM in some cases [14]

doi: 10.1038/s41598-022-17244-6 32 CandelloneAGirolamiFBadinoPJarriyawattanachaikulWOdoreR

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