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Methods 14 , 417 (2017)

Prolonged exposure and quantity of cigarette smooke by smokers did not cause depletion of antioxidants among active smokers

Oxidation stress is the imbalance between oxidants and antioxidants in favour of the oxidants, potentially leading to damage

While the study found no significant differences in the primary efficacy endpoint (time to first tolerated meal), the ipamorelin group showed reduced median time to first tolerated meal (25.3 hours versus 32.6 hours in placebo) and had fewer overall treatment-emergent adverse events (87.5% versus 94.8%)