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However, existing studies primarily focus on short-term intervention effects at the cellular and animal levels, with a notable absence of comprehensive long-term behavioral assessments and safety evaluations

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Protective effects of lycium ruthenicum murray against acute alcoholic liver disease in mice via the nrf2/ho-1/nf-b signaling pathway

In hyperuricemia management, synthetic gene networks integrating HucR-based biosensors and secreted Aspergillus flavus urate oxidase achieve self-regulated urate degradation, dynamically adjusting enzyme expression to maintain physiological UA levels while avoiding excessive urate depletion (Kemmer et al., 2010)

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