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Most Common Tesofensine Side Effects The side effects reported most frequently include: Dry mouth Insomnia or disrupted sleep Nausea Constipation Headache Occasional diarrhea In clinical trials, participants taking a common 0.5 mg dose experienced an average increase in heart rate of about 7 beats per minute

PubMed: (peer-reviewed) Lee S, et al

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The compound has been evaluated in multiple preclinical models for its role in modulating adipose tissue and lipid metabolism without mimicking the full spectrum of hGH activity (Heffernan et al

One of the most promising is PT-141, a therapy that works directly on the brains arousal centers rather than only focusing on physical performance