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ALA competes with linoleic acid for metabolic space, leading to a decrease in the level of arachidonic acid, as well as the quantity of class II PG and leukotrienes in tissue phospholipids (Reference Cambiaggi, Chakravarty and Noureddine38)

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Rahmi EP, Kumolosasi E, Jalil J, Buang F, Jamal JA (2022) Extracts of Andrographis paniculata (Burm.f.) Nees leaves exert anti-gout effects by lowering uric acid levels and reducing monosodium urate crystal-induced inflammation

This is why it is important to select an area with a sufficient pinch of fat, such as the abdomen (at least two inches away from the belly button), the front of the thighs, or the back of the upper arm