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Saffrons pharmacology (boosting dopamine/serotonin) means one should use caution if combining it with other serotonergic substances (like antidepressants such as SSRIs) to avoid any risk of serotonin overload

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This suggests the peptide may have cardioprotective properties, though human data remains limited

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Compared to histamine-2 receptor antagonist, proton pump inhibitor induces stronger oral-to-gut microbial transmission and gut microbiome alterations: a randomised controlled trial [J]