(2017) Guideline for Primary Care: Investigation and management of B12/folate deficiency

B12 has many functions in our body, so unfortunately a deficiency will give rise to a wide variety of symptoms, like brain fog, memory problems, cognitive impairment, insomnia, headaches, especially migraine, behavioural changes, learning problems, nominal aphasia, mood swings, irritability, depression, anxiety, hallucinations, delusions, psychosis, peripheral paraesthesia (pins and needles), numbness, neuropathic pains, poor balance, reduced vibration sense or proprioception (joint position sense), tinnitus, ataxia, taste impairment, sometimes myelopathy, fatigue, anaemia (either with larger red blood cells, or with normal size of the red blood cells when there is also iron deficiency), other reduction in blood cells, abdominal complaints, malabsorption, failure to thrive, weight loss, diarrhoea, hyperpigmentation, glossitis, (aphthous) stomatitis, infertility, urinary tract infections, joint and muscle pain, muscle weakness, spasticity, seizures, cardiomyopathy, urinary and/or faecal incontinence, postural hypotension/dizziness, erectile dysfunction, to name a few

As people age, they sometimes have trouble absorbing vitamin B12, even when taking pills by mouth, which is when vitamin B12 injections may be considered
Here, increased vitamin B12 levels seem to occur much less frequently than in the previously mentioned diseases
Each 10 mL multi-dose vial contains 100 mcg/mL of Vitamin B12, equivalent to ten 1 mL weekly injections, making it a convenient and cost-effective option for patients requiring regular supplementation