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Without this cross-linking step, new collagen is fragile and prone to re-injury

Am J Respir Cell Mol Biol 39:105112

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3.5 HHcy in PCOS Preliminary investigations in observational and randomized controlled trials have indicated that women with PCOS exhibit higher serum homocysteine (Hcy) levels, along with higher levels of markers of CVDs, such as hs-CRP, soluble CD40 ligand (sCD40L), and asymmetric dimethylarginine (ADMA) than did healthy controls (211, 212)

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