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Some preliminary clinical trials have also been conducted

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In addition, resveratrol increases dystrophin expression, downregulates the expression of muscle atrophy-associated proteins, including atrogin-1, MuRF-1, and myostatin through enhancing the interaction between SIRT1 and FoxO1, thereby alleviating muscle atrophy

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The average age of the study population was 13 years, with nearly half (46%) of the patients being female and white (53.8%)