[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Amrein K., Scherkl M., Hoffmann M., Neuwersch-Sommeregger S., Kstenberger M., Tmava Berisha A., Martucci G., Pilz S., Malle O
This may be unsurprising, given the primary role of glutamine in glutamate recycling, a process likely to be cortex-wide
The hallmark of this condition is a cycle of chronic inflammation
Among them, C-X-C motif chemokine ligand 1 and 2 (CXCL1 and CXCL2) are significantly upregulated in lesional skin and primarily mediate neutrophil recruitment through interaction with the CXCR2 receptor, thereby aggravating tissue damage and acute symptoms such as erythema and edema (Sakai et al., 2021)
While research suggests promising benefits, long-term data on its effects in humans remains limited