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It is possible that other substances synthesized from POMC were the underlying cause of increased activity in Pomc -overexpressing animals

13, 20, 26, 27, 48, 70, 71, 72 They are actively taken up into the brain 73 and can affect diverse physiological processes such as cell signaling, 71 neurotransmitter synthesis and release, 70 mitochondrial function, 20 lipid metabolism, 13, 74 immune function, 75 cellcell interactions 76 and gene expression

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A request has been submitted to create a multicounty litigation (MCL), which is a group lawsuit representing people who developed NAION