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Glutathione may reduce chemotherapy efficacy, particularly with platinum or alkylating agents

The basis of this increased ATP content of older cells is thought to be due to an age-related decrease in adenylic acid deaminase (adenosine monophosphate [AMP] deaminase), an enzyme that irreversibly degrades AMP to inosine 5-monophosphate

Hosseini B, Nourmohamadi M, Hajipour S, et al

Thankfully, most short-term studies have reported no major side effects, which is reassuring for people curious about trying it

Serum glutathione peroxidase, xanthine oxidase, and superoxide dismutase activities and malondialdehyde levels in patients with Parkinsons disease