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Feeling constantly tired, mentally foggy, or struggling with low motivation can often be traced back to a nutrient deficiencymost commonly vitamin B12

Moderate deficiency: Those with moderate cases usually get a standard dose, about 1,000 mcg

For suspected macro-B12, precipitation with PEG is the test most often reached for, though it is nonspecific and can remove B12 that is fully available to cells, so direct measurement of the binding proteins, haptocorrin and transcobalamin, may be more informative when it is available

By the time it's recognized that you have B12 deficiency, you probably only realize your levels are lower now than they've been for some time now