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Mathew N, Misra-Bhattacharya S, Perumal V, Muthuswamy K (2008) Antifilarial lead molecules isolated from Trachyspermumammi

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Although M2 polarization is generally associated with tissue repair, it exerts pro-tumor effects in established cancers (132)

With these points in mind, we undertook a broad assessment of published clinical data, curating the body weight loss (% from baseline), glycosylated hemoglobin levels (HbA1c), and nausea responses (% patients reporting) from the SUSTAIN 3, SUSTAIN 7, SCALE Diabetes, SURPASS 2, and STEP 2 trials (17, 22, 64, 66, 67) ( Figures 1AC )